Addiction as Entrenchment
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With an account, you can revise, criticize, and comment on ideas.My Conjecture
Conjecture: addiction is the result of the entrenchment of a conflict between two or more preferences in a mind.
Picture a smoker who wants to give up smoking but also really enjoys smoking. Those preferences conflict.
If the conflict is entrenched, then both preferences get to live on indefinitely. The entrenchment will not let the smoker give up smoking. He will become a chain smoker.
Solutions for the conflict may need to be found creatively, case by case. It depends on the nature of the particular entrenchment and the preferences involved. A more overarching answer for how to cure addiction might involve Randian ideas around introspection and getting one’s reason and emotions in the proper order.
There is a similar (identical?) theory put forward by Marc Lewis in The Biology of Desire. He explains addiction as the process of "reciprocal narrowing". The process of reciprocal narrowing does not remove conflicting desires, but instead reinforces a pattern of dealing with conflict through a progressively narrower, habitual response (substance, action, mental dissociation). Addiction, therefore, as you suggested, is a process of managing the "conflict between two or more preferences within the mind."